Opportunity Information: Apply for PAR 22 115
The Research on Community Level Interventions for Firearm and Related Violence, Injury and Mortality Prevention (CLIF-VP) opportunity (PAR-22-115) is a National Institutes of Health (NIH) funding announcement aimed at building practical, evidence-based ways to prevent firearm and related violence by working at the community or community-organization level. The program is grounded in the view of violence as a major public health crisis that affects people across the lifespan, with especially severe consequences for young people and for populations that are often disproportionately harmed, including racial and ethnic minority communities, sexual and gender minority (SGM) populations, and people with disabilities. The announcement highlights the seriousness of the problem by noting that firearm homicide is the third leading cause of death among individuals ages 10 to 24, and that firearm mortality is especially high for Black men in mid-adulthood. Consistent with NIH policy and legal constraints referenced in NOT-OD-21-058 and NOT-OD-21-056, the focus is on prevention-oriented research that can reduce violence, injury, and death without straying into prohibited areas.
This initiative is designed to support a network of research projects that do more than describe the problem; applicants are expected to develop and test interventions that operate at a community scale or within community-serving organizations. In practice, that can include strategies delivered through local institutions and settings where prevention can realistically be implemented and sustained, such as community-based organizations, schools, health systems, housing-related entities, faith-based organizations, or other local infrastructures. The emphasis on community-level action signals NIH interest in approaches that can shift environments, systems, and local conditions that shape risk and safety, rather than interventions aimed only at individuals in isolation.
The award uses the UG3/UH3 Phased Innovation mechanism under a cooperative agreement structure. In a cooperative agreement, NIH typically has substantial programmatic involvement compared to a standard grant, which often means more active collaboration, milestone tracking, and coordination across funded projects to build a coherent research network. The project itself is bi-phasic. The UG3 phase (Phase I) is essentially a start-up and readiness period where the research team must demonstrate that key elements are in place: feasibility, operational capacity, partnerships, and other foundations needed to run a rigorous community intervention study. Applicants must propose specific aims and clearly defined milestones for both phases from the start, not just a general plan. Successful completion of UG3 milestones is the gatekeeper for moving forward; projects that meet those predefined targets can be administratively considered for transition to the UH3 phase (Phase II), which is the implementation and testing phase where the larger-scale intervention evaluation occurs. The FOA also notes that clinical trials are optional, meaning applicants may propose a design that meets the NIH definition of a clinical trial if appropriate, but they are not required to do so.
Eligibility is broad and intentionally inclusive, spanning many types of U.S.-based organizations that can lead or partner on community violence prevention research. Eligible applicants include state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; tribal organizations other than federally recognized governments; public housing authorities and Indian housing authorities; nonprofit organizations with or without 501(c)(3) status; for-profit organizations other than small businesses; and small businesses. The announcement also explicitly encourages participation from institutions and organizations that often serve populations most impacted by violence, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs). It also calls out faith-based and community-based organizations, as well as certain eligible federal agencies and regional organizations, reflecting a strong interest in real-world implementation partners with deep community ties.
At the same time, the FOA is explicit about limits related to foreign involvement. Non-domestic (non-U.S.) entities and non-domestic foreign institutions are not eligible to apply, and non-domestic components of U.S. organizations are not eligible. In addition, foreign components as defined in the NIH Grants Policy Statement are not allowed. In other words, projects must be fully domestic in institutional footprint and execution, even if they draw on international evidence or frameworks.
Administrative details in the source information identify NIH as the sponsoring agency, with the funding instrument categorized as a discretionary cooperative agreement and the activity category listed under Education, Health, Income Security and Social Services. Multiple CFDA numbers are associated with the opportunity (93.213, 93.242, 93.273, 93.279, 93.307, 93.313, 93.361, 93.865, 93.866), reflecting NIH’s cross-institute structure and the possibility that multiple NIH components participate in supporting the initiative. The original closing date listed is 2022-04-22, and the record creation date is 2022-03-04. An award ceiling and expected number of awards are not specified in the provided text, so applicants would typically look to the full FOA or NIH Guide notice for budget guidance, institute-specific interests, and any updates.
Overall, CLIF-VP is structured to move promising community violence prevention ideas from readiness and feasibility into real-world testing, while holding teams accountable to concrete milestones before they scale. The program’s design strongly favors applicants who can show authentic community partnerships, credible implementation settings, and a plan for producing evidence that can inform community-level prevention practice and policy within NIH’s statutory boundaries.Apply for PAR 22 115
- The National Institutes of Health in the education, health, income security and social services sector is offering a public funding opportunity titled "Research on Community Level Interventions for Firearm and Related Violence, Injury and Mortality Prevention (CLIF-VP) (UG3/UH3 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.213, 93.242, 93.273, 93.279, 93.307, 93.313, 93.361, 93.865, 93.866.
- This funding opportunity was created on 2022-03-04.
- Applicants must submit their applications by 2022-04-22. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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